GENE PANELS

STHT - GYNAECO PANEL

DETAILS

 
Version :
Status :
Size :
Website :
3.1
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65 genes
Extra info :
Method :

Capture based panel, using the Roche KAPA HyperPlus kit and KAPA HyperChoice probes

CERTIFICATES

 
141-MED (UZ Brussel)
141-MED (UZ Brussel)

INSTRUMENTS

 
Illumina NovaSeq 6000
Illumina NovaSeq 6000

Our highest capacity short read sequencer. This device can generate reads up to 250 bp in length (on the SP flowcell) and generate up to 10B reads per flowcell (S4).

DOWNLOADS

 
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Genelist STHT gynaeco

3.1

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STHT subpanels overview

3.1

CONTACT

 
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Secretariaat Medische Genetica

+32 (0)2 477 64 79 (sec)

UZ Brussel

Centrum Medische Genetica

Laarbeeklaan 101

1090 Brussels

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Freya Vaeyens

+32 (0)2 477 64 79 (sec)

UZ Brussel

Centrum Medische Genetica

Laarbeeklaan 101

1090 Brussels

SAMPLE TYPES

 

We aim to keep te list with sample types updated. However, if you believe we offer this gene panel on other sample types, of if you have a very specific sample type you'd like to evaluate : please contact the corresponding persons for either diagnostic or research purposes.

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Tissue
Recipient
Quantity
Transport
Purpose / Extract
Blood
EDTA tube
10 ml (min. 3 ml)
Room temperature
DNA
DNA from various tissues
Microtube*
See test details/specifications
Room temperature
DNA
DNA from various tissues
Microtube* or 96 well plate
See test details/specifications
Room temperature
DNA
FFPE block of various tissues
Paraffin block (in cassette)
Representative block ; Tumor load preferentially >10% ; To be processed by our pathology department (microtome section needed)
Room temperature
DNA
FFPE section of various tissues
Microtube*
Min. 1x 10 µm section (up to 2 mm³ tissue) ; Tumor load preferentially >10%
Room temperature
DNA
Tissue of various origins
Cryovial containing stabilizer (eg. AllProtect) or tissue homogenized on lysis buffer
Application/tissue specific (contact us)
Dry ice
DNA

* Microtube can be  a either a cryovial or eppendorf tube (0,5 ; 1,5 or 2 ml). Please consider the quality of the tube used (nuclease free ; free of RNA/DNA ; sterile ; LoBind) according to application needed.  

DELIVERABLES

 

Which data files can be retrieved from us for this specific gene panel?

Deliverable
Description
Research or diagnostic
Called variants - vcf file
Text file containing all detected variants as compared to the relevant reference genome
Diagnostic / RUO
Clinical report
Diagnostic report generated by Clinical Geneticist/ Pathologist
Diagnostic
Raw data - bam file
Binary data file containing the aligned reads
RUO (on request)
Raw data - fastq file
Data file containing the raw (unaligned) reads
RUO (on request)
Run folder
The complete run folder can be transferred if it concerns a run reservation (private run)
RUO (on request)
 

GENELIST

AKT1
ALK
ANKRD26
AR
ARID1A
ATM
BARD1
BRAF
BRCA1
BRCA2
BRIP1
CDH1
CHEK1
CHEK2
CTNNB1
DICER1
DPYD
EGFR
ERBB2
ERBB3
ERBB4
ESR1
FGFR1
FGFR2
FGFR3
FLT3
FOXL2
IL7R
KEAP1
KIT
KRAS
MLH1
MSH2
MSH6
MTOR
NBN
NF1
NF2
NTRK1
NTRK2
NTRK3
PALB2
PDGFRA
PDGFRB
PIK3CA
PMS1 (MLH2)
PMS2 (MLH4)
POLD1
POLE
PTEN
PTPN11
RAD51B
RAD51C
RAD51D
RAD54L
RAF1 (CRAF)
RB1
ROBO1
ROBO2
STK11
TENT5C (FAM46C)
TP53
TSC1
TSC2
USP13