INSTRUMENTS

A grasp of the BRIGHTcore instrumentation. is listed below. Click on the corresponding 'Read more' button to find more about the applications, principle and sponsors / owners.

MPS / NGS

Illumina MiSeq

Our lowest capacity short reads sequencer, able to generate reads up to 300 bp in length and this at a throughput of 1M to 30M reads per run.

DNA/RNA QUALIFICATION

AATI Fragment Analyzer

Capilary electrophoresis device that enables qualification and quantification of (genomic) DNA samples, but also RNA samples.

DNA/RNA QUANTIFICATION

Perkin Elmer DropletQuant

High throughput UV-Vis spectrometer for the quantification of DNA, RNA and proteins

DNA FRAGMENTATION

Diagenode BioRuptor Pico

Medium throughput (6 - 12 samples) DNA fragmentation device resulting in high quality fragmentation results using low cost plastics.

ARRAY

Illumina iScan

Medium throughput SNP array device, where 4 beadchips can be scanned/loaded simultaneously. The amount of samples that can be loaded is dependent on the assay/beadchip.

LIQUID HANDLING

Gilson Platemaster P220

Manual 96-channel air-displacement pipette from Gilson to manipulate large sample quantities in 96 or 384-well plates. As it is a manual pipette, it is highly versatile in usage in lab.

MPS / NGS

Illumina NovaSeq 6000

Our highest capacity short read sequencer. This device can generate reads up to 250 bp in length (on the SP flowcell) and generate up to 10B reads per flowcell (S4).

DNA/RNA QUALIFICATION

Caliper LabChip GXII

Microchip electrophoresis device that enables speedy qualification of DNA samples of up to 6Kb in size.

DNA/RNA QUANTIFICATION

Perkin Elmer Victor Nivo 3F

High throughput fluorescence, luminescence and absorbance (filter based) plate reader.

DNA SIZE SELECTION

Sage Science Pippin Prep

Low throughput methodology for perfoming very tight DNA size selections, that are not possible using magnetic beads.

SINGLE-CELL APPLICATIONS

10x Genomics Controller

Microdroplet generator to partition single cells and to barcode RNA/DNA using the 10x Genomics Next GEM technology.

MPS / NGS

NanoPore GridION x5

Sequencing long reads is no hassle on this device. It can sequence 5 MinION flowcells simultaneously and perform the data analysis on board.

DNA/RNA QUANTIFICATION

Invitrogen Qubit 2.0

Basic fluorometer for single-tube concentration measurements of dsDNA, ssDNA, RNA and proteins

DNA FRAGMENTATION

Covaris M220

Low throughput DNA fragmentation device (single tube). High quality fragmentation results, but costly tubes required.

ARRAY

Affymetrix GeneChip 3000

Medium throughput SNP array device, where 48 samples (1 sample/genechip) can be processed simultaneously per run.

LIQUID HANDLING

Formulatrix Mantis

Automated liquid handler, requiring virtually no plastics/tips. It dispenses (incrementally) droplets of 0,1 or 0,5 µl for the Low volume chip and 1 or 5 µl droplets for the High volume chip. It is solely used to pipette reagents (virtually no 'dead volume') and not biological samples.